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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T25017 | AKT-I-1 | Akt | |
AKT-I-1 is a selective and reversible inhibitor of Akt1. | |||
TP1528 | Angiotensin I/II (1-5) | Angiotensin I/II 1-5 | RAAS , Others |
Angiotensin I/II (1-5) is a peptide (ASP-ARG-VAL-TYR-ILE) that contains the amino acids 1-5 and is converted from Angiotensin I/II. | |||
TP1579 | Angiotensin I/II (1-6) | Angiotensin I/II 1-6 | RAAS , Others |
Angiotensin I/II (1-6) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS) that contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. | |||
TP1705 | Gastrin I (1-14), human | Others | |
Gastrin I (1-14), human, represents the 1-14 peptide fragment of human gastrin I, an endogenous gastrointestinal peptide hormone. This compound is the principal hormonal regulator of gastric acid secretion. | |||
T2457 | IRAK-1-4 Inhibitor I | IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor | IRAK |
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1. | |||
TP1122L | IGF-I 30-41 acetate(82177-09-1 free base) | Insulin-like Growth Factor I (30-41) acetate | Others |
IGF-I 30-41 acetate(82177-09-1 free base) (Insulin-like Growth Factor I (30-41) acetate) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). | |||
T37696 | NOS1-IN-1 | nNOS Inhibitor I | NOS |
NOS1-IN-1(nNOS Inhibitor I) is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).NOS1-IN-1 has a Ki value of 39 μM for eNOS and 325 μM for iNOS.NOS1-IN-1 can be used for the study of neurological disorde... | |||
T7637 | Deltorphin I | Deltorphin 1,Deltorphin I(TFA),Deltorphin C | Opioid Receptor |
Deltorphin I is an agonist of δ-opioid receptor. | |||
T36622 | Angiotensin I/II (1-6) (TFA) | ||
Angiotensin I/II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I/II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angi... | |||
T22136 | PRL-3 Inhibitor I | PRL-3 Inhibitor,BR-1 | Phosphatase , Others |
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. | |||
TP1295 | Angiotensin I (human, mouse, rat) | Angiotensin 1 Human | Others |
Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE).Angiotensin is a peptide hormone that causes vasoconstriction and an in... | |||
T2045 | JANEX-1 | Jak3 inhibitor I,WHI-P131 | JAK |
JANEX-1 (Jak3 inhibitor I) is a cell-permeable, reversible, effective, ATP-competitive, and selective inhibitor of JAK3 (IC50: 78 μM); little inhibitory against JAK1/2, or Zap/Syk or SRC tyrosine kinases. | |||
T4191 | Multi-kinase inhibitor 1 | Multi-kinase inhibitor I | Others , Bcr-Abl , PDGFR , c-Kit |
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor. | |||
TP1643 | Alpha 1(I) Collagen (614-639), human | ||
This is a peptide inhibitor of collagen fibrillar matrix assembly. | |||
T32104 | Hras-1Y i-motif Probe-1 | ||
Hras-1Y i-motif Probe-1 is a probe of the hras-1Y i-motif which selectively and directly interacts with it. | |||
TP1287 | Gastrin I (1-14), human TFA | ||
Gastrin I (1-14), human TFA is 1-14 fragment of human gastrin I peptide. | |||
T8746L | I-49 free base | Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-,I-49 | Raf |
I-49 free base (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-) is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibito... | |||
TP2447 | Angiotensin I, asn(1)-val(5)-gly(9)- | ||
Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata. | |||
T6583 | MG-101 | ALLN,Ac-LLnL-CHO,Calpain inhibitor I,Calpain inhibitor-1,MG101 | Cysteine Protease , Proteasome |
MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. | |||
T6859 | I-BRD9 | GSK602 | Epigenetic Reader Domain |
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3. | |||
TP1121 | IGF-I (30-41) TFA(82177-09-1,FREE) | Insulin-like Growth Factor I (30-41) (TFA) | |
IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). | |||
T8955 | PCNA-I1 | Others | |
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer. | |||
T1906 | Molibresib | GSK 525762A,GSK525762,I-BET 762 | Epigenetic Reader Domain |
Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM). | |||
T3984 | GLP-1(7-36), amide | MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide | Glucagon Receptor |
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-... | |||
T7084 | 2-Bromo-4'-hydroxyacetophenone | SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide | Phosphatase |
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH... | |||
T3049 | TPCA-1 | GW683965,IKK2 Inhibitor IV,TPCA1 | Apoptosis , IκB/IKK , STAT |
TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes. | |||
T1830 | BX795 | IκB/IKK , Chk , CDK , c-Kit , PDK , Autophagy | |
BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than... | |||
T7951 | TBK1/IKKε-IN-5 | IκB/IKK | |
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively). | |||
T15559 | TBK1/IKKε-IN-2 | IκB/IKK | |
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε. | |||
T6513 | Bisindolylmaleimide I | GF109203X,Go 6850 | PDGFR , PKC |
Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM. | |||
T131467 | 1-Hydroxylbaccatin I | ||
1-Hydroxylbaccatin I is a useful organic compound for research related to life sciences and the catalog number is T131467. | |||
T32327 | Juvocimene I | Juvocimene 1 | |
Juvocimene I and II isolated from the essential oil of sweet basil,Ocimum basilicum L are potent juvenile hormone mimics. | |||
T31360 | Deepoxy-deoxynivalenol | DOM-I,DOM-1 | |
Deepoxy-deoxynivalenol is Metabolite of deoxynivalenol. Deepoxydeoxynivalenol is a macrocyclic polyol compound for proteomics research. Environmental contaminants; Food contaminants. | |||
T62048 | Topo I-IN-1 | ||
Topo I-IN-1 (Compound 14d) is a potent Topo I inhibitor. Topo I-IN-1 exhibits antitumor activity and DNA intercalative capability. Topo I-IN-1 can induce cell apoptosis. | |||
T61720 | Pol I-IN-1 | ||
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition concentration (IC50) of 0.21 μM [1]. | |||
T36170 | A1-Phytoprostane-I | A1-Phytoprostane-I | |
A1-Phytoprostane-I is a cyclopentenone isoprostane produced by the action of reactive oxygen species on α-linolenic acid in plants. There are two A1-phytoprostanes, both having the single ketone group on the ring structu... | |||
T64153 | Glyoxalase I inhibitor 1 | ||
Glyoxalase I inhibitor 1 is a potent inhibitor of glyoxalase I (GLO1) (IC50: 26 nM). | |||
T63557 | HCA I-IN-1 | ||
hCA I-IN-1 is a human carbonic anhydrase I (hCA I) inhibitor that acts on hCA I (Ki: 38.3 nM), hCA II (Ki: 716.4 nM), hCAIX (Ki: 940.1 nM) and hCAXII (Ki: 192.8 nM). | |||
T25970 | Polymyxin B1-i | ||
Polymyxin B1-i is a polypeptide antibiotic. | |||
T81373 | Proteasome β2c/i-IN-1 | Proteasome | |
Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1]. | |||
T23869 | WEE1-IN-4 | Wee1-Inhibitor-I,Wee1 Inhibitor-I,Wee1 Inhibitor I,Wee1-Inhibitor I | |
Wee1 Inhibitor I is an ATP-binding site-targeting Wee1 inhibitor. | |||
T7461 | 2,4-Diamino-6-hydroxypyrimidine | DAHP | Reactive Oxygen Species , NO Synthase |
2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis | |||
T39591 | Human PD-L1 inhibitor I | Human PD-L1 inhibitor I | |
Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1. It exhibits a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 i... | |||
T0097 | MRT67307 | MRT67307 HCl | IκB/IKK , Autophagy |
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage... | |||
T26378 | 1-Benzyl-I3C | ||
1-Benzyl-I3C is an NEDD4-1 inhibitor. | |||
T29909 | ALS-I | ALS1,Acid-Liable Surfactant-1,ALS 1,ALS-1 | |
ALS-1 is an acid-Liable surfactant. | |||
T9105 | NF-κB-IN-1 | 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)- | IκB/IKK , NF-κB |
NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir... | |||
T60450 | AChE/hCA I/II-IN-1 | ||
AChE/hCA I/II-IN-1 (Compound 6) is a potent AChE/Hca inhibitor with IC50 values of 22.21, 60.79 and 66.64 nM for AChE, Hca Ⅰ and Hca Ⅱ. AChE/hCA I/II-IN-1 can be used in glaucoma, Alzheimer's disease, and diabetes rsearc... | |||
T61939 | Topo I/COX-2-IN-1 | ||
Topo I/COX-2-IN-1 (1H-30) is a potent Topo I/COX-2 inhibitor with the IC50 of 0.24 μM and 4.42 μM for COX-2 and Topo I, respectively. Topo I/COX-2-IN-1 induces apoptosis and inhibits migration of cancer cells, shows anti... | |||
TP1021 | Urocortin, human | Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I | CRFR |
Urocortin, human (Human urocortin I) is a 40 amino acid peptide which is closely related to corticotrophin-releasing factor (CRF). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2540 | 1-Hydroxybaccatin I | Others | |
1-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions. | |||
T12090 | Mogroside I E1 | Others | |
Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. | |||
T2715 | Tubeimoside I | Tubeimoside-1,Lobatoside-H | Apoptosis , Others |
Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM). | |||
T3895 | Polyphyllin I | Apoptosis , Akt , JNK , PDK , mTOR , Autophagy | |
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha... | |||
T6S2123 | Ginkgolic Acid | Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),Ginkgolic acid C15:1 | Others , E1/E2/E3 Enzyme |
Ginkgolic Acid (Romanicardic acid) C15:1 represses curli genes and prophage genes in EHEC. | |||
T12089 | Mogroside I A1 | Others | |
Mogroside I A1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, exhibiting antioxidant, antidiabetic and anticancer activities. | |||
T2961 | Notoginsenoside R1 | Sanqi glucoside R1,Sanchinoside R1 | Apoptosis , ERK , Beta Amyloid |
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties. | |||
T23645 | Aeroplysinin 1 | NSC170364,Aeroplysinin I,NSC 170364,NSC-170364 | |
Aeroplysinin I is an antibacterial compound from the sponge. It has cytotoxic activity against colon cancer cells by promoting β-catenin degradation. | |||
TN5997 | Stipuleanoside R1 | Tarasaponin I | |
Stipuleanoside R1 is a natural product for research related to life sciences. The catalog number is TN5997 and the CAS number is 96627-79-1. | |||
T6856 | Halofuginone | Tempostatin,empostatin,RU-19110 | Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal. | |||
T3524 | Halofuginone hydrobromide | Tempostatin,RU-19110 (hydrobromide),Stenorol | Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad |
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce... | |||
TN7117 | Regaloside I | Others | |
Regaloside I is the monomeric component in lily. Regaloside I could be the main constituent in protecting human dermal fibroblasts from UVA-induced morphological changes [1]. | |||
T3S1227 | Aristolactam I | Aristolactam,Aristololactam I,Aristololactum | Apoptosis , Caspase |
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF... | |||
T5S2076 | Senkyunolide I | Others , Caspase | |
1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties. | |||
T3S1892 | Crassicauline A | Crassicauline I | Others |
1. Crassicauline A (Crassicauline I) and Yunaconitine possesses feeding deterrent activity against T. castaneum adults, with EC(5) values of 1134.5 and 653.4 ppm, respectively. | |||
T2873 | Ginsenoside Rg2 | Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2 | Beta Amyloid , GSK-3 , NF-κB |
Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor. | |||
TN1420 | Bacopaside I | Others | |
Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ... | |||
T10233 | Acetylarenobufagin | HIF | |
Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator. | |||
T5S0167 | Atractylenolide I | IL Receptor , TNF , TLR , JAK , STAT | |
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide... | |||
T3S0335 | Soyasaponin Bb | Soyasaponin I | NF-κB , Caspase |
1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa... | |||
T5S1262 | Methylophiopogonanone A | Others | |
1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulati... | |||
T4A2458 | Resibufogenin | Bufogenin,Recibufogenin | Others |
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff... | |||
T3S2072 | 3-Butylidenephthalide | Butylidene phthalide,n-Butylidenephthalide | Parasite , Glucosidase |
1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitiv... | |||
T3S1873 | Talatisamine | Potassium Channel | |
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat... | |||
T3S0057 | Dihydrochelerythrine | 12,13-Dihydrochelerythrine | Antifungal |
1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ... | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
TCS1704 | Artemitin | Artemetin,Artemisetin,Erianthin | Antioxidant |
1. Artemitin (Erianthin) has anti-inflammatory activity. 2. Artemitin (Erianthin) protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. 3. Intravenou... | |||
TN2080 | Pinoresinol | (+)-Pinoresinol | Apoptosis , NF-κB , CDK , p53 |
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st... | |||
T5S1632 | Barlerin | 8-O-Acetylshanzhiside methyl ester,ND01 | VEGFR , TNF , NF-κB , Akt , Caspase |
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e... | |||
TN4661 | Nodosin | IL Receptor , Autophagy | |
Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp... | |||
T5S0527 | Rhodojaponin III | Others | |
1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception of Rhodojaponin III and played a critical role. 2. Rhodoja... | |||
T2S1792 | Lycobetaine | Ungeremine | Antibacterial |
1. Lycobetaine (Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Lycobetaine have strong antibacterial activity against Flavobacterium columnare . 3. Lycobetaine effectively... | |||
T6S1418 | Praeruptorin C | Antioxidant , Calcium Channel | |
1. Praeruptorin C has been widely used as an antioxidant and a calcium antagonist to treat diseases. 2. Praeruptorin C partially protects cortical neurons by inhibiting the expression of GluN2B-containing NMDA receptors ... | |||
TCS2170 | 2,5-Dihydroxyacetophenone | Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP | ERK , NF-κB , Tyrosinase |
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK... | |||
T5S0053 | Coptisine | Coptisin | Indoleamine 2,3-Dioxygenase (IDO) |
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ... | |||
T6S1369 | Vitexin | Apigenin-8-C-glucoside | Antioxidant |
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit... | |||
T3339 | Sophoridine | 5-Epidihydrosophocarpine,Dihydro-5-episophocarpine | Apoptosis , Topoisomerase |
Sophoridine (Dihydro-5-episophocarpine), a natural anticancer drug, has been used in China for decades. A series of novel N-substituted Sophoridinic acid derivatives were synthesized and evaluated for their cytotoxicity ... | |||
T2830 | Betulinic acid | ALS-357,Lupatic acid,Betulic acid | Apoptosis , Mitophagy , NF-κB , HIV Protease , Topoisomerase , Endogenous Metabolite , Aminopeptidase , Autophagy |
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has antiretroviral, antimalarial, and anti-inflammatory propert... | |||
T4S2326 | Cornuside | 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside | ERK , p38 MAPK , NF-κB , JNK |
1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi... | |||
T6S1572 | Sauchinone | ERK , p38 MAPK , NF-κB | |
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T81765 | Monofucosyllacto-N-hexaose I | MFLNH I | |
Monofucosyllacto-N-hexaose I (MFLNH I) constitutes a human milk oligosaccharide (HMO) [1]. | |||
T83378 | 2-Methoxy-6-pentadecyl-1,4-benzoquinone | ||
2-Methoxy-6-pentadecyl-1,4-benzoquinone (1c), a pentadecyl derivative, is isolatable from seed oils of various Iris species, including I. pseudacorus, I. missouriensis, and I. sibirica [1]. | |||
TN5675 | Ganomycin I | ||
Ganomycin I inhibits the activity of HIV-1 protease. | |||
T81920 | LNnDFH I | Lacto-N-neo-difucohexaose I | |
LNnDFH I, a natural product, can be isolated from human urine [1]. | |||
T81887 | Macrostemonoside I | ||
Macrostemonoside I, a furostanol saponin, can be isolated from Allium macrostemon [1]. | |||
T81961 | Lacto-N-difucohexaose I | LDFH I | |
Lacto-N-difucohexaose I (LNDFH I), a connecting agent, may facilitate the attachment of Lewis b sugar chain-bearing oligosaccharides to water-insoluble polysaccharides [1]. | |||
TN1169 | 1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside | 1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-beta-glucopyranoside | Topoisomerase |
1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-beta-glucopyranoside may have DNA topoisomerases I and II inhibitory activity and cytotoxicity. | |||
T81020 | Tenaxin I | ||
Tenaxin I, an extract from Radix Scutellariae, exhibits neuraminidase inhibitory activity [1]. | |||
T82690 | Complanatin I | ||
Complanatin I, a natural product, is isolated from Astragalus complanatus [1]. | |||
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Cat No. | Product Name | Species | Expression System |
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TMPY-02899 | Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and... | |||
TMPY-03855 | DNase I Protein, Human, Recombinant (His) | Human | HEK293 |
DNase1, also known as deoxyribonuclease I and DNL1, is a member of the DNase family. DNaseI is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phos... | |||
TMPY-06982 | IGF1/IGF-I Protein, Human, Recombinant | Human | E. coli |
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I... | |||
TMPY-02767 | TPP1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit... | |||
TMPY-00695 | I-309 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 d... | |||
TMPY-04853 | TSHR Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Thyroid-stimulating hormone (TSH) is secreted by the pituitary gland and promotes thyroid growth and function, with increased TSH levels typically associated with hypothyroidism. Immunohistochemical analysis revealed pre... | |||
TMPY-04878 | IGF1/IGF-I Protein, Mouse, Recombinant | Mouse | Yeast |
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I... | |||
TMPY-02553 | Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (aa 1-264, hFc) | Mouse | HEK293 |
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and... | |||
TMPY-04625 | SEMA3A Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 5 aa Sema domain. They are best characterized in relation to axon guidance during development of the nervous sys... | |||
TMPK-00305 | TGFBR1 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup... | |||
TMPY-02956 | Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney... | |||
TMPK-00678 | CALCA/CGRP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a... | |||
TMPY-01168 | ALK-1 Protein, Human, Recombinant (His) | Human | HEK293 |
Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. ... | |||
TMPY-01047 | IL-1R1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPY-02371 | ST6GAL1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type I... | |||
TMPY-00834 | IGF1R/CD221 Protein, Human, Recombinant (His) | Human | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPY-04774 | ALK-2/ACVR1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
ALK-2, also termed as ACVR1, was initially identified as an activin type I receptor because of its ability to bind activin in concert with ActRII or ActRIIB. ALK-2 is also identified as a BMP type I receptor. It has been... | |||
TMPY-00124 | SEMA3A Protein, Human, Recombinant (hFc) | Human | HEK293 |
Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 5 aa Sema domain. They are best characterized in relation to axon guidance during development of the nervous sys... | |||
TMPY-01459 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-02142 | IL-1R1 Protein, Rat, Recombinant (His & mFc) | Rat | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPJ-00702 | APT-1 Protein, Human, Recombinant (His) | Human | E. coli |
Acyl-Protein Thioesterase 1 (APT-1) is lysophospholipase that belongs to the AB hydrolase 2 family. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. APT-1... | |||
TMPY-05215 | TPP1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit... | |||
TMPY-03688 | IL-1R1 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPY-03744 | IL-1R1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPY-02059 | IL-1R1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPJ-00731 | Carbonic Anhydrase 1 Protein, Human, Recombinant (His) | Human | E. coli |
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 p... | |||
TMPY-03449 | CPNE1 Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
Copine I, also known as CPN1, is a member of the copine family. Copine I is a calcium-dependent membrane-binding protein which has a wide tissue distribution. Calcium-dependent membrane-binding proteins may regulate mo... | |||
TMPY-03265 | CPNE1 Protein, Human, Recombinant (SUMO) | Human | Baculovirus-Insect Cells |
Copine I, also known as CPN1, is a member of the copine family. Copine I is a calcium-dependent membrane-binding protein which has a wide tissue distribution. Calcium-dependent membrane-binding proteins may regulate mo... | |||
TMPJ-01142 | CDO1 Protein, Human, Recombinant (His) | Human | E. coli |
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pan... | |||
TMPJ-01291 | CPNE1 Protein, Human, Recombinant (His) | Human | E. coli |
Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not co... | |||
TMPJ-00158 | Apolipoprotein A-I/APOA1 Protein, Human, Recombinant | Human | E. coli |
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various... | |||
TMPY-06955 | Apolipoprotein A-I/APOA1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and... | |||
TMPY-04942 | IGF1 LR3 Protein, Human, Recombinant | Human | Yeast |
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I... | |||
TMPJ-00789 | Flagellin Protein, Salmonella Typhimurium, Recombinant | Salmonella typhimurium | E. coli |
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin... | |||
TMPJ-00528 | PPP1R1A Protein, Human, Recombinant (His) | Human | E. coli |
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein pla... | |||
TMPK-01291 | ANXA1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPK-00768 | ANXA1 Protein, Human, Recombinant (His) | Human | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPK-00799 | ANXA1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ... | |||
TMPJ-00814 | RBP1 Protein, Human, Recombinant | Human | E. coli |
Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. Retinol and retinoic acid play crucial roles in the modulation of gene expression and overall d... | |||
TMPK-00774 | TrkA Protein, Human, Recombinant (aa 33-417, His) | Human | HEK293 |
TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signa... | |||
TMPY-01158 | CD38 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPY-06651 | CD38 Protein, Mouse, Recombinant | Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu... | |||
TMPJ-01311 | EPT1 Protein, Human, Recombinant (GST) | Human | E. coli |
Ethanolaminephosphotransferase 1 (EPT1) is an enzyme that belongs to the CDP-Alcohol Phosphatidyltransferase Class-I Family. EPT1 is a Selenoprotein, which contains a Selenocysteine (Sec) residue at its active site. The ... | |||
TMPH-03258 | Carbonic Anhydrase 1 Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Reversible hydration of carbon dioxide. | |||
TMPH-00223 | Alpha-S2-casein Protein, Bovine, Recombinant (His & KSI) | Bovine | E. coli |
Important role in the capacity of milk to transport calcium phosphate.; Casocidin-I inhibits the growth of E.coli and S.carnosus. | |||
TMPJ-00240 | CAMK1 Protein, Human, Recombinant (His) | Human | Human Cells |
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed.... | |||
TMPY-00320 | APOA1BP Protein, Human, Recombinant (His) | Human | HEK293 |
APOA1BP, now renamed NAXE, encodes an epimerase essential in the cellular metabolite repair for NADHX and NADPHX. The enzyme catalyzes the epimerization of NAD(P)HX, thereby avoiding the accumulation of toxic metabolites... | |||
TMPJ-01176 | SEMA4C Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. P... | |||
TMPY-02729 | IL-1R1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
TMPY-02341 | IL-1R1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This pro... | |||
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